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- Sharkarosa Ranch
- Sharon Arts Center
- Sharon Lynne Wilson Center for the Arts
- Sharon S Richardson Community Hospice Inc
- Sharons Arms
- Sharsheret Inc
- Shasta Sky Sailors
- Shaw Pit Bull Rescue
- Shawnee Trail Wild Mustang Sanctuary
- Shaykwan And Kenyatta Open Arms Inc
- She Angels Foundation
- She Believes In Me
- She Is Safe
- SHE Will Foundation of Central Texas
- Sheep Dog Impact Assistance
- Sheep Gate Inc
- Sheets From Home Inc
- Sheila Tolbert Ministries, Inc.
- Shekinah Gloria Ministries, Inc.
- Sheldrick Wildlife Trust USA
- Shelter Animal Resource Alliance
- Shelter Animals Advocates
- Shelter Animals Count
- Shelter Association of Washtenaw County
- Shelter Dog Transport Alliance
- Shelter From The Storm Animal Rescue
- Shelter Ministries Inc
- Shelter Music Boston
- Shelter On The Hill A Humane Society
- Shelter Partnership Inc
- Shelter Providers Of Houston Inc
- Shelter Transport Animal Rescue Team
- SHELTER, Inc.
- SHELTERBOX USA
- Sheltering Hands Inc
- Shenandoah Community Foundation Inc
- Shenandoah Shepherd Rescue
- Shenandoah Valley Conservancy (formerly Valley Conservation Council)
- Shenandoah Valley Discovery Museum, Inc.
- Shenandoah Valley Music Festival
- Shepherd & Mother of Light for the Needy
- Shepherd Fund
- Shepherd's Center of Northern Virginia
- Shepherd's Center of WS
- Shepherd's Door Domestic Violence Resource Center
- Shepherd's Hope, Inc.
- Shepherds Arms Rescue Mission Inc
- Shepherds Fold Ministry Inc
- Shepherds Gate
- Shepherds Heart Ministries Inc
- Shepherds Hill Academy
- Shepherds Refuge-Selah Ministries Inc
- Sherbro Foundation Sierra Leone
- Sheridan Carroll Charitable Works Fund Inc
- Sheriffs & Police Activities League Of Memphis & Shelby County
- Shia Muslim Council Of Southern California
- SHIELD 616
- Shield Bearer
- SHIELDS for Families
- Shift Today Ministries Inc
- Shifting Gears United Inc
- Shikshan ane Samaj Kalyan Kendra
- Shiloh Adventures
- Shimmy Club Inc
- SHINE ( Society For Helping Integrity Network For Empowerment)
- Shine Bright Ministries Inc
- Shine Foundation
- Shining Hope for Communities
- Shining Light Community Development Organization
- Shining Light Homes
- Shining Light In Darkness
- Shining Stars Sports Academy
- Shining Warrior
- Shipyard Trust For The Arts
- Shir Chadash Conservative Congregation
- Shirley Ann Sullivan Educational Foundation
- Shirley Chisholm Cultural Institute
- Shirley Heinze Land Trust, Inc
- Shirley Proctor Puller Foundation
- Shirley's Way Inc.
- Shjon Podein Childrens Foundation
- Shoebox Ministry, Inc.
- Shoes That Fit
- Shoot Basketballs Not People
- Shopping for a Change
- Shore Animal Volunteer Enterprise Inc
- ShoreLake Arts
- Shores of Grace Ministries
- Short & Stumpy Pups Inc
- Short Bowel Syndrome Foundation, Inc.
- Short Moments
- Short Mugs Rescue Squad
- Show Mercy International
- Shree Maharishi Bhrigu Ashram
- Shreveport-Bossier Rescue Mission
- Shri Krishna Nidhi Foundation Inc
- Shrimad Rajchandra Love and Care - USA
- Shrimad Rajchandra Mission Dharampur (USA)
- Shriners Hospitals for Children
- Shriners Hospitals for Children — Salt Lake City