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- INTRACRANIAL HYPERTENSION RESEARCH FOUNDATION
- Intrepid Fallen Heroes Fund
- Intrepid Museum Foundation, Inc.
- InvestigateWest
- Invictus Institute
- Invisible Children Inc.
- Invisible Disabilities Association
- Invisible People
- InvisiYouth Charity
- ioby
- Iowa City Free Medical Clinic
- Iowa Farm Sanctuary
- Iowa Human - Animal Bond Society
- Iowa Humane Alliance
- Iowa Parrot Rescue
- Iowa Pet Alliance Foundation
- Iowa Voters For Companion Animals
- IPaintMyMind
- Ipswich Equine Rescue Corp
- Ipswich River Watershed Association Inc
- Iranian American Medical Association
- Iranian American Women Foundation
- Iraq And Afghanistan Veterans Of America Inc
- Iraq Rose Inc
- Iraqi Children's Hope
- Iredell County Humane Society Inc
- Iresq Rr
- Irie Kids Inc
- Iris Global
- Irish Repertory Theatre Company Inc
- Iron County Care and Share
- Iron Freedom Foundation
- Iron Gait Percherons Inc. - Draft Horse Rescue
- Iron Lives Inc
- Iron Men Outdoor Ministries Inc
- Iron Sharpens Iron
- Iron Soup Historical Preservation Co
- IRON THERAPY INC.
- Irondog K9 International Inc
- Irvine Nature Center
- Irvine Public Schools Foundation
- Irving Art Of Science
- Irving Cares
- Irving Schools Foundation
- Irwin and Florence Rosten Foundation
- Isaiah Alonso Foundation
- Isaiahs Place
- ISchool
- ISCI FOUNDATION
- ISG Cares
- Isha Foundation Inc
- Islamic Center Masjid-Al-Sabereen
- Islamic Center Of Maryland Inc
- Islamic Medical Association Of North America
- Islamic Relief USA
- Islamic Research and Development Foundation
- Islamic Sufi Order Of Qadiri Rifai Tariqa Of The Americas
- Islamic Ummah Relief
- ISLAMINSPANISH INC
- Island Dolphin Care
- Island Friends Roatan Inc
- Island Safe Harbor Animal Sanctuary Inc.
- Islands Society
- Islands Society
- Isles, Inc.
- Israel Cancer Association Usa
- Israel Guide Dog Center
- Israel Longhorn Project
- Israel Scholarship Education Foundation
- Israeli Chamber Project Inc
- ISSAC ORG INC (International School for Science and Culture)
- iStart Valley
- Istoria Ministry Group
- IT TAKES TWO INC
- It's A Military Life Corporation
- It's a She Thing, Inc.
- It's About the Kids Education Organization Inc
- It's From the Heart Inc.
- It's Meow or Never Animal Rescue Sanctuary
- IT4Causes
- Italian Greyhound Rescue Foundation Inc
- Itasca County Family Young Mens Christian Association Inc
- Its A Shell Thing Inc
- ITS HUH Ministry (In The Streets-Hands Up High Ministry)
- Its Just Benign Inc
- Its Meow Or Never For Ferals Inc
- Its the Pits
- Its Time Texas
- Its Your Best Shot
- Itty Bitty Kitty Inc
- Ivanhoe Neighborhood Council
- Ive Been Mended Inc
- IVolunteer International Inc
- Ivy Child International Inc
- IVY HILL Therapeutic Equestrian Center
- Ixcanul Foundation
- Izi Azi Foundation dba/ Felicia's Farm
