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- Encompass
- Encore Stage & Studio Inc
- enCourage Kids Foundation
- End Violence Against Women (EVAW) International
- Endabuse4good Inc
- Endangered Species International
- Endangered Wolf Center
- Endometriosis Association, Inc.
- Endometriosis Research Center and Women's Hospital, Inc.
- Endowment Fund – Meals On Wheels, Inc. of Tarrant County
- Enduring Hearts
- Energy and Sciences Academy Inc
- Energy Outreach Colorado
- Engaging Creative Minds
- EngenderHealth, Inc.
- English River Outfitters Resort
- English Springer Rescue America Inc
- Enlightened Warriors Boys Girls Of Virtue And Purpose
- Enrichment Audio Resource Services, Inc.
- Enrichment Circle Inc.
- Enrichment Works
- Enter Stage Left Theater, Inc.
- Enter Stage Right, Inc
- Enterprise for High School Students
- Entertainment With A Mission Charity Inc
- Entito Africa Initiative, Kenya
- Environment California Inc
- Environmental and Energy Study Institute (EESI)
- Environmental and Spatial Technology Inc
- Environmental Defense Fund Incorporated
- Environmental Fund for Arizona
- Environmental Law & Policy Center Of The Midwest
- Environmental Law Alliance Worldwide - ELAW
- Environmental Learning for Kids
- Environmental Support Center Inc
- Environmental Volunteers, Inc.
- Environmental Working Group
- Envision Children
- Envision Minnesota
- Envision Mission Church
- Envision Performing Arts Inc
- Enyi Md Foundation Inc
- EOTO World
- Ephraims House
- Epic Experience
- Epilepsy Association of Central Florida Inc
- Epilepsy Association of Utah
- Epilepsy Foundation of Arizona
- Epilepsy Foundation of Greater Chicago
- Epilepsy Foundation of Minnesota Inc
- Epilepsy Foundation of Texas - Houston/Dallas/Ft.Worth/West Texas
- EPILEPSY INSTITUTE OF NORTH CAROLINA
- Epilepsy Services Foundation, Inc.
- Episcopal Childrens Services Inc
- Episcopal Communities Foundation, Inc. dba Episcopal Place
- EPISCOPAL HOUSING FOUNDATION INC dba Episcopal Place
- Episcopal Relief and Development
- Epitome of Soul Inc.
- Epona Horse Rescue Inc
- Eppic Ministries International, Inc.
- Equal Justice Center
- Equal Justice USA Inc
- Equality Florida, Inc.
- Equamore Foundation
- Equestrian Connection NFP
- Equestrian Inc.
- Equi-Ed, Inc.
- Equi-Kids Therapeutic Riding Program
- Equi-Librium Therapy Center
- Equilibrium Dynamics
- Equine 808 Horse Rescue
- Equine Advocates Incorporated
- Equine Aid
- Equine Assistance Project, Inc.
- Equine Dreams
- Equine Land Conservation Resource
- Equine Outreach, Inc.
- Equine Partners Unlimited Inc
- Equine Rescue and Adoption Foundation, Inc.
- Equine Rescue Inc
- Equine Rescue of Aiken
- Equine Rescue Resource Inc
- Equine Wellbeing Rescue Inc.
- Equus Medendi Inc
- Equus Survival Trust
- Erectile Dysfunction Foundation
- Erica Raes Kids Inc
- Erie Area Rabbit Society & Rescue E A R S Inc
- Erie Homes for Children and Adults Inc
- Erie Trap and Release
- Erika's Lighthouse: A Beacon of Hope for Adolescent Depression
- Erowid Center
- Esophageal Cancer Action Network, Inc. (ECAN)
- Esperanca, Inc.
- Esperanza-Hope
- Esposas Militares Hispanas USA Armed Forces
- Essential Health Clinic
- Estancia Corazon Inc
- Estill County 21st Century, Inc. DBA Estill Development Alliance
- ETA4
