Quantum Leap Health Carecollaborative

Programs: I-spy 2 (investigation of serial studies to predict your therapeutic response with imaging and molecular analysis 2) is a clinical trial for women with new diagnosed locally advanced breast cancer. The trial tests whether adding investigational drugs to standard chemotherapy is better than standard chemotherapy alone before having surgery. The treatment phase of this trial tests multiple investigational drugs that are thought to target the biology of each participant's tumor. Quantum leap has made significant financial investment in this important trial, as a co-project manager, and continues to adapt the design to improve the quality of the data obtained. Quantum is exploring additional processes to allow patients who have not responded to one drug to participate in the trial for other investigational drugs under study that may prove beneficial to the patient.

calm (collaboratory for accelerating learning in medicine) is a project to transform the practice of medicine. Using a holistic approach, the project looks to align the processes of clinical care and research by integrating information and workflow processes to accelerate decision-making through a provider portal. The project aims to change how future leaders in medicine are educated, as well as develop policies and reimbursement mechanisms that support integrated medical care and better outcomes. Quantum leap is utilizing the onesource data platform to support the provider portal through electronic data capture, with the intent to create interactive health care management systems that provide comprehensive information for improved health care and allow patients to report outcomes to fully integrate the learning experience. Quantum leap is working with research and educational institutions, as well as commercial entities, in this process

bctmatch: breastcancertrials. Org is an online service that helps patients find breast cancer trials personalized to their situation by matching their histories to trial eligibility criteria. Bctmatch is a customizable, technology platform that supports clinical trial matching across all cancers. The boston veteran's administration medical center is using bctmatch to support its lung cancer clinical trial matching application.

athena network (www. Athenanetwork. Org) is a very large, multi-state project within the university of california. Athena's mission is to track up to 150,000 women with breast cancer over a long period of time to find genetic markers for breast cancer. Quantum leap has been providing project management and technology expertise to athena since its inception. I-spy 1 network utilizes i-spy clinical trial methodology to bring new pharmaceutical agents into the system, assuring that they meet safety qualifications for further testing in the phase 2 and 3 trials in a more efficient and effective manner. I-spy 3 is intended to be a phase 3 clinical trial to continue to test whether adding investigational drugs to standard chemotherapy is better than standard chemotherapy alone before having surgery.