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Causes: Biological & Life Sciences
Mission: Ncgr is a 501(c)(3) nonprofit research institute that applies bioinformatics, software engineering, and next-generation sequencing to solve the pre-eminent challenges of 21st century biology through collaborative research and services. Independently and in partnership with other science and technology leaders, ncgr is dedicated to supporting the health and food security of future generations.
Programs: Genomics and bioinformatics: programs in this area are 1) legume information system and network-a legume bioinformatics resource (usda), 2) science tools in the classroom (stc) - bioinfomatics, genomics and more (nih), 3) assembly and analysis of complex plant genomes (private funding), 4) federated plant database initiative for the legumes (nsf), 5) single cell transcriptomics in plands (gordon and betty moore foundation), 6) new tools for pan-genomics across phylogenetic space (nsf), 7) sequence resources for cotton, a model system for allopolyploid crops (nsf), 8) deciperhing molecular basis of elite red alder lines and their frankia alni symbionts (nsf), 9) biofilm resource and information database (braid) - a tool to fuse diverse biofilm data types (nsf), 10) structural variation of diploid and polyploid plant genomes (nsf).
dna and rna sequencing: this program includes studies to understand 1) the root nodule bacerial community involved in nitrogen fixation for the north american deciduous tree red alder, 2) genetic markers in maize and soybean, 3) genetic diversity in the model legume medicago truncatula, 4) underlying progression of alzheimer's disease pathogenesis to identify novel therapeutic targets, 5) genetic biomarkers for severe malaria, 6) clinically-relevant fetal immunobiology in malaria-endemic regions, 7) coronavirus in alaskan bats, 8) genes involved in metabolic, endocrine and immune responses in growth and recovery of weddell seal skin. Studies to develop 1) a sequencing method for plants to uncover a deeper level of understanding at the single cell level (moore), 2) a genome assembly of a drought tolerant cotton species g herbaceum.