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- EIN 52-2044704
- (301) 547-2900
- Po Box 2352 Germantown MD 20875 USA
- www.aeras.org
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Nonprofit Overview
Causes: Health, International, International Development, Specifically Named Diseases Research
Mission: Aeras is a non-profit product development organization dedicated to the development of effective tuberculosis (tb) vaccines and biologics to prevent tb across all age groups in an affordable and sustainable manner. Aeras utilizes its broad capabilities and technologies in collaboration with numerous partners and stakeholders to support the development of vaccines and other biopharmaceuticals to address tb and other significant public health needs of underserved populations. In the pursuit of our mission, we are guided by our core values. These core values express our aspirations and the behaviors we want to exhibit and model. They shape the culture and character of aeras and inform all of our decisions and actions.
Programs: Preclinical - aeras develops and assesses a range of vaccine platforms and variations, and explores novel approaches to enhance the effectiveness of new tb vaccines in effective prime-boost regimens. Aeras evaluates tb vaccine candidates to determine whether they have the characteristics needed to move forward to the next phase of development. Key elements include evaluation of safety, immunogenicity and the protection the candidates provide in animal models. An independent panel of vaccine experts evaluates all relevant preclinical data before a candidate is approved for entry into phase i trials. Aeras also supports the assessment of novel assays that could be implemented at the clinical stage of development to drastically reduce the time and cost of developing new vaccines against tuberculosis.
clinical - aeras and its research partners have transformed the tb vaccine clinical landscape. Six vaccine candidates are undergoing testing in clinical trials in kenya, senegal, south africa, the united kingdom, and the united states with support from aeras for protocol development, safety monitoring, regulatory and immunology. We also design and conduct epidemiology studies to estimate tb prevalence and/or incidence under real-world trial conditions to inform ongoing studies and to assess the feasibility of conducting large-scale clinical trials in tb at additional research sites in tb endemic countries, including china.
aeras also works to build relationships that support its goal to develop tb vaccines through collaboration at the global and regional levels with multi-lateral organizations such as the european union, the european investment bank, and the world health organization, among other tb researchers and vaccine developers, as well as with donors, advocates and policymakers who can help raise awareness and support for this work. Aeras' scientific and external affairs departments are critical to advancing these strategic partnerships to ensure global support.
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This organization's nonprofit status may have been revoked or it may have merged with another organization or ceased operations.