Programs: Program activities related to childhood obesity: hopelab refocused its efforts to scale the impact of its zamzee product, an evidence-based technology product designed to measure and motivate physical activity in kids and families as a way to combat the trend toward sedentary behavior and obesity in the u. S. (www. Hopelab. Org/zamzee). An earlier large-scale randomized controlled impact trial of zamzee indicated that middle-school-aged adolescents using zamzee experienced an average increase in moderate-to-vigorous physical activity (mvpa) of 59% or approximately 45 additional minutes of mvpa per week compared to a control group. The product launched as part of a for-profit social enterprise, zamzee co. , established by hopelab in 2011; however, hopelab determined that philanthropic resources would be required to sustain development and delivery of the zamzee product to consumers. In 2014 hopelab dissolved zamzee co. , with staff and operations re-integrated into hopelab as a department do program activities related to cancer: hopelab continued distribution and marketing activities to support use of its evidence-based re-mission 2 online games and mobile app designed to support treatment adherence in teens and young adults with cancer; re-mission 2 is the newest iteration of hopelabs original re-mission video game released in 2006. The games are publicly available free of charge at the product website administered by hopelab (www. Re-mission2. Org), and the app is available as a free download via google play and itunes. Hopelab actively promoted re-mission 2 to young cancer patients, clinicians and health professionals, and the general public through conferences, speaking engagements, and social media marketing activities and continued to disseminate insights from re-mission/re-mission 2 research in order to catalyze broad development of evidence-based tools for social benefit.