MASONIC MEDICAL RESEARCH LABORATORY

Results: Heart Disease is a Killer Cardiac arrhythmias claim more lives than any other form of heart disease and are responsible for Sudden Cardiac Death (including some instances of SIDS) associated with inherited syndromes like the long QT, short QT and Brugada as well as sudden cardiac arrest occurring after a heart attack. The most prevalent cardiac arrhythmia, atrial fibrillation (AF), affects 1 in 20 individuals at age 65 and 1out of 5 individuals at age 80. AF reduces the quality of life form millions of Americans and is one of the leading causes of stroke in the United States. The good news is that the Cardiac Research Institute at Masonic Medical Research Laboratory (CRI/MMRL) is conducting research aimed at developing knowledge needed to combat these deadly and debilitating diseases. We are internationally renowned as one of our country’s leading cardiac research centers and highly respected and referenced within the scientific and medical community worldwide. The MMRL is a recognized international center for genetic screening of cardiac diseases, especially those involving inherited cardiac arrhythmias. OUR SCIENTIFIC LEGACY HAS generated new heart medications; most recently for atrial fibrillation, helped to develop diagnostic procedures for the management of cardiac arrhythmias and most importantly aided in the advancement of life-saving technologies. OUR CARDIAC RESEARCH includes studies focused on regenerative medicine and development of human models of disease using an exciting new technology employing induced pluripotent stem cells, which precludes the need for use of embryos. Stem Cell research has tremendous potential in designing and discovering new drugs, new treatments and even cures based on root/genetic cause which will change the face of medicine as we know it today. YOU NEED TO KNOW that 84 cents of every dollar is used for cardiac research. Your gift helps to ensure the health of future generations; perhaps saving the life of a loved one or even your own. We also train and educate tomorrow’s scientists, clinical researchers and physicians. OPTIONAL Dr. Charles Antzelevitch, MMRL executive director, was named 2011Distinguished Scientist of the Year by the American Cardiology. CRI scientists authored the chapter on mechanism of cardiac arrhythmias in Hurst’s the Heart, a leading reference book used by cardiologists worldwide. www.mmrl.edu Federal Tax ID: 13-5648611 New York State Charities Registration: 037227 Florida Charities Registration: CH-36722

Programs: The Masonic Medical Research Laboratory (MMRL) is an internationally recognized biomedical research institute. For its size, there are few institutes worldwide whose cutting edge research is as productive and influential in the field of experimental cardiology. In recent years, the MMRL has become an international center for genetic screening of cardiac arrhythmia diseases, especially those contributing to sudden death syndromes, including sudden infant death syndrome (SIDS). The MMRL is blazing new trails in the development of safe and effective drugs for atrial fibrillation, addressing one of the greatest unmet medical needs facing our society. With its recent inauguration of a Stem Cell Center, the MMRL is making rapid progress in the creation of human models of disease focused on development of innovative therapies and cures.