Mission: Jacob’s Cure is a 501c3, non-profit foundation that was created in September 2000. Jordana Holovach is the Founder and Director of Jacob’s Cure. She created the foundation because of her passion to save the life of her son, Jacob, who is afflicted with Canavan disease, a fatal genetic brain disorder. The sole mission of Jacob’s Cure is to fund research in Canavan disease that aims to cure thousands of children dying of Canavan disease today. Jacob’s Cure allocates monies raised to research, this is made possible due to volunteer staff and minimal overhead. Areas of research include gene-therapy, stem cell transplantation, pharmacological approaches and basic science in understanding the pathways of the disease. Because Canavan is a rare disorder, federal funding is scarce. It is through the efforts of Jacob’s Cure and the philanthropy of others that enables Canavan research to continue and a cure for Canavan a hopeful reality.
Results: To date, Jacob’s Cure has funded two gene-therapy trials and is currently funding research towards a phase 1 stem-cell clinical trial aimed for 2011. Research efforts to date have slowed down and in some cases halted the progression of the disease in most of the children who received gene-therapy and have begun the recommended pharmacological regimen.
Programs: University of medicine & dentristry of new jersey $49,500 umass medical school $100,000 heartbeat lifesharing $250
Jacob is magical and Jordana his mother is a real go getter. Please watch the video and see how much progress has been made in the treatment of this brain disease through Jacob's cure and how this science can help other too. The quality of life of these children and their families is improving all the time. It still takes a tremendous amount of effort and money to keep moving forward. Please give generously to Jacob's Cure and know that not one cent of your money or time will go to waste. You can feel proud that you you are helping families and improving the future of health care for us all.