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Causes: Health, Nerve, Muscle & Bone Diseases Research
Programs: Brown cartilage (cartilage repair & regeneration program)patients, whose activities are limited due to arthritic knees but whose pain is not yet severe enough to warrant a total knee replacement, face a paucity of treatment options. The articular cartilage replacement program has successfully developed a novel minimally invasive device to replace the lost and damaged cartilage and bone in the medical condyle and the patella of the knee in these patients. This program began with a thorough literature search and anatomic studies of the knee. An analysis of the economic optimization for treatments for the knee was also undertaken to assess the viability of various novel approaches. Next, a series of prototype implants and instruments were developed to meet the design criteria of the implants for both the medical condyle and the patella. Once the design was finalized, programs of extensive mechanical testing and in vivo animal study were under taken. Brown prosthesis (direct to skeleton attachment prosthesis program)recovery from an amputation is a long and complex process, often producing less than desirable results. Even a rehabilitation that is termed successful will often involve complications such as residual limb skin breakdown, pain and poor control of the prosthetic limb. The prosthetic attachment program has sought to develop a prosthetic limb in which an implant within the residual limb reacts with the prosthetic socket to provide a stable, non-contact connection between the patient and the prosthesis. The interaction of the specially designed magnetic system results in a system of forces, by which the prosthesis and the patient's skeleton are held in mechanical equilibrium, eliminating pain and soft tissue complications associated with traditional limb prostheses.