Mission: Honoring military service with science; our bench-to-bedside approach has led to breakthroughs in areas such as shingles prevention, heart disease, metabolic diseases and ground breaking work on post-traumatic stress disorder.
Programs: Dr. Hammond - discovery and development of therapeutic genes for chf. The purpose of this program, "discovery & development of therapeutic genes for chf," is to enable a number of scientists at vmrf and ucsd to maintain an efficient, interactive and mutually reinforcing program of basic and translational research to promote the discovery and development of therapeutic genes for congestive heart failure (chf) and other cardiovascular diseases. The program will facilitate the transition from discovery to clinical application of new therapeutic genes. This model combines discovery research with practical "street-smart" preclinical development. Successfully attaining our goals will require separate but highly integrated projects that contain the proper proportions of discovery research and focused preclinical development, an accomplished translational physiology core, and an interactive group of vmrf and ucsd physician-scientists in an ideal environment.
dr. Thorp - in-home exposure therapy for veterans with ptsd. Exposure to combat and other traumatic events results in a variety of negative physical and mental health outcomes, including posttraumatic stress disorder (ptsd). Ptsd impacts veterans, veterans' families, and society more globally. Efficacious exposure therapies, such as prolonged exposure therapy (pe), have been developed to reduce the severity of ptsd symptoms. However, research indicates that these interventions are underutilized due to issues such as stigma and transportation difficulties. Even when treatment is initiated, the rates of premature dropout are high. Telehealth (using electronic communications technology to provide care from a distance) and home-based care offer compelling alternatives to traditional office-based care. Home-based care, in particular, offers the advantage of treating veterans within their typical environment. This allows therapists to observe factors that may be critical to the success of exposure therapies (e. G. , how best to approach feared situations in or near the home) while helping veterans generalize the skills he or she has learned in treatment.
dr. Granholm-enhancing assertive community treatment with cbt and sst for schizophrenia. Recent public health interest has focused on recovery-oriented mental health services for the treatment of functional disability in severe mental illnesses like schizophrenia. Evidence-based practices have been identified and recommended in best practice guidelines, but these practices are rarely available to most people with schizophrenia. This study, directed by dr. E. Granholm, will attempt to close the gap between research and service delivery by testing the effectiveness of evidence-based psychosocial interventions that have been adapted for practical delivery by community clinicians in real-world clinical settings. From a public health standpoint, delaying institutionalization, reducing unnecessary or premature hospitalizations, and increasing patients' contributions to the community, should have significant personal, societal, and economic impact.
veterans medical research foundation of san diego, where we honor service with science, is the region's only medical research institute dedicated to veterans. We facilitate world-class research at the va san diego healthcare system that provides improvements for veterans' healthcare. While focused on veterans, our medical advances extend to the entire population and raise the standard of care for everyone.