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2019 Top-Rated Nonprofit

Cancer Research Institute, Inc.

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Nonprofit Overview

Causes: Cancer, Cancer Research, Health, Medical Disciplines Research

Mission: Save more lives by fueling the discovery and development of powerful immunotherapies for all types of cancer.

Results: Immunotherapy has begun to transform cancer treatment. Medicines that unleash the immune system have enabled many patients to live longer, healthier lives. Checkpoint blockade, CAR T cell therapy, and oncolytic virus therapy has received FDA approval to treat a variety of cancers, including lung, colorectal, bladder, skin, head and neck, and kidney cancers as well as melanoma, lymphoma, and leukemia. For many decades since its founding in 1953, the Cancer Research Institute was the only nonprofit organization to believe immunotherapy could one day save lives. That day has come, and it's just the beginning. Immunotherapy has potential to treat nearly all forms of cancer. With continued research, we can learn to increase the effectiveness of these treatments so that more and eventually all patients benefit. CRI is committed to funding the most promising research, wherever it's being done, to accelerate the pace of progress and save more lives sooner.

Target demographics: Under the leadership of our Scientific Advisory Council, which includes 4 Nobel Laureates and 26 members of the National Academy of Sciences, CRI funds academic research in immunology and tumor immunology at universities and health research centers around the world.

Direct beneficiaries per year: Approximately 300 scientists and clinicians in 18 countries

Geographic areas served: National, International

Programs: The CRI Irvington Postdoctoral Fellowship Program furthers career development and supports laboratory research for promising young scientists working under the mentorship of leading immunologists. The Anna-Maria Kellen Clinical Accelerator is a unique nonprofit-academia-industry partnership model designed to develop, organize, and de-risk clinical study of next-generation combination cancer immunotherapies. The Clinic and Laboratory Integration Program (CLIP) grants provide catalytic support for translational laboratory studies designed to answer new specific scientific questions that arise in the clinic, with special focus on improving immunotherapy for cancer patients. The Lloyd J. Old STAR Program (Scientists TAking Risks) provides grants of $1.25 million over 5 years to mid-career scientists. This long-term funding will not be tied to a specific research project, but rather provides a degree of flexibility and freedom for investigators to explore out-of-the-box and disruptive avenues of research. The CRI Technology Impact Award provides seed funding of up to $200,000 to be used over 12-24 months to address the gap between technology development and clinical application of cancer immunotherapies. CRI's Impact Grants support research projects and public education and awareness initiatives for which funds have been specifically raised.

Community Stories

100 Stories from Volunteers, Donors & Supporters

Professional with expertise in this field

Rating: 5

Cancer Research Institute has top-level senior scientists in cancer and immunology fields to steer funding towards researchers and projects that have high potential to make new breakthroughs in cancer immunotherapy. Thank you, CRI !

Professional with expertise in this field

Rating: 5

The Cancer Research Institute (CRI) is an amazing organization that provides me with an unparalleled platform to conduct my research in cancer immunotherapy. In addition, CRI has given me a great opportunity to reach out to and collaborate with other outstanding scientists in this field. Importantly, as an international postdoc, I am most grateful for CRI’s decision to support merit-based research for scientists with diverse backgrounds or nationalities. Thank you CRI!

Professional with expertise in this field

Rating: 5

The Cancer Research Institute is an amazing organization that provides critical support to both basic and translational research aimed at harnessing the immune system to fight cancer. Funding from the CRI has been integral to my postdoctoral research and has further fueled my passion for cancer immunotherapy. For this, I am extremely grateful and would like to thank the CRI and its many donors for their continued dedication and support to young immunologists and the field of cancer research.

Jason Jun R.

Professional with expertise in this field

Rating: 5

Curing cancer is my dream. I have had the great fortune to receive support from the Cancer Research Institute (CRI) and work as a postdoctoral researcher at Massachusetts General Hospital and Harvard Medical School. The generous support from CRI provides me an extraordinary opportunity to explore how the immune system fights tumors and develop novel strategies to overcome resistance to current therapies, and most importantly, bring hope to cancer patients! Thank you, Cancer Research Institute!

Professional with expertise in this field

Rating: 5

I am an early career scientist focusing on tumor immunity. CRI provides essential support for my research. In addition to financial support, CRI provides numerous opportunities for training and collaboration. I am thrilled to be a part of the CRI community.

Previous Stories

Professional with expertise in this field

Rating: 5

I am an early career scientist with a research interest in tumor therapy. CRI has provided essential support to help me establish an independent research program and explore new research directions. The application process for CRI funding is straightforward. In recent years, with limited federal funding, financial support from nonprofits, such as CRI is critical for the discovery of new therapies for cancer patients.

Professional with expertise in this field

Rating: 5

The Cancer Research Institute has been funding postdoctoral fellows in my laboratory for a number of years now and I am very grateful for their contribution to my research. The peer review process for their fellowship and grant programs is very rigorous and their support is amazing. The support CRI provides to Fellows to collaborate and network in the broad field of immunological and cancer research is crucial for their career development.
The vision CRI had when starting to promote the involvement of the immune system in cancer research is truly remarkable and has led to several breakthroughs in the way we treat this devastating disease.

1 May G.

Professional with expertise in this field

Rating: 5

I'm a young scientist who is eager to help fighting cancers by doing basic research. With a three-year postdoctoral fellowship from Cancer Research Institute, I’m hoping to dissect the complexity of signaling in the tumor environment and help improve therapeutics for all cancers. I really appreciate CRI's generous support in cultivating the future of cancer research, and its effort bringing the fruit of science to the patients.

Professional with expertise in this field

Rating: 5

As a CRI-sponsored post-doctoral fellow, CRI is playing critical roles in my scientific career. CRI does not only provide me with a stipend, but also exposes me to great ideas from other fellows and senior scientists during the annual conference. Cancer is still a devastating disease, but the CRI community is trying best to conquer cancer.

Client Served

Rating: 5

Thanks to the Cancer Research Institute, I've been awarded with essential funding to research essential aspects of cancer biology. I'd like to highlight, that they fund translational research as well as basic research. This demonstrates that their criteria to select grantees are based on expert scientific views. Thank you for many discoveries to come!

Advisor

Rating: 5

I am an Australian cancer immunology research scientist and The Cancer Research Institute has funded my research on and off for more than a decade. Their funding is peer reviewed and well considered across many programs, including those funding early career scientists. They were responsible for the annual meetings in this area of research since 2000 and I met virtually all of my most important collaborators from all over the world in the field at these meetings. Their web site has been one of the best public educational tools in the field. Their leadership has been brilliant and their staff loyal, friendly and helpful over all of those years. In summary they have greatly enriched my career and provided the world great service.

Professional with expertise in this field

Rating: 5

CRI is a big support for my postdoctoral research. I am studying the gene regulatory network of T cell development, which is essential to understand cancer immunobiology. Without the funding from the CRI, I would not be able to fully focus on the factors that I am working now. I am so grateful for CRI's work to support basic science and translational researches!

Lewis L L.

Professional with expertise in this field

Rating: 5

CRI was the FIRST charity to dedicate their mission to advancing engaging the immune system to fight cancer. They have supported hundreds of young scientists and physicians to bring them into this field that has transformed cancer therapy. An absolutely amazing organization that is totally dedicated towards curing cancer using your own immune system.

Professional with expertise in this field

Rating: 5

CRI funding has been transformative for the field of cancer immunotherapy and is driving major innovation in the field. Our lab's funding from CRI is enabling us to take big risks and push forward in new directions that we hope will continue to expand the reach of immunotherapies to treat cancers that are not yet responding to therapies. I am profoundly grateful for CRI's tireless work to promote fundamental inquiry and clinical translation of immunotherapy.

Volunteer

Rating: 5

The Cancer Research Institute (CRI) is an amazing nonprofit offering a plethora of Immunotherapy resources to gain knowledge, stay updated, seek Clinical Trial offerings and to connect with fellow cancer patients/caregivers/medical personnel. CRI funds promising Immunotherapy research that is changing the cancer treatment landscape and is saving and changing lives. Knowledge is power and as a Patient Advocate, I have been fortunate to participate as a Patient Speaker and attend several of their annual Immunotherapy Patient Summits. I am always in awe of the Researchers and Doctors asked to share their work at the Patient Summits. Knowledge, Hope, Inspiration and Support is transpired to all those that attend the annual Patient Summits. I applaud CRI for all that they do and for funding Immunotherapy Research so that I could still be here alive today!

Volunteer

Rating: 5

Cancer Research Institute is the oldest non profit organization focusing on immunotherapy and funds the best scientists in the field . By sharing my story and experience with immunotherapy CRI has given me a chance to give back and share hope with other patients. Their Immunotherapy Patient Summits are free educational events that give patients access to experts in the field and advocates who have been treated with immunotherapy. Knowledge is empowering when faced with a cancer diagnosis. Clinical trial navigators are available to assist patients in discovering trials that may benefit them. Cancer Research Institute is a trusted source of information for patients who want to learn more about immunotherapy and it’s potential.

Michael A. C.

Client Served

Rating: 5

CRI sponsored my lab's research looking into how tumor hypoxia (low oxygen concentration) created a barrier that helped make prostate and pancreatic cancer almost totally immune to the FDA-approved immunotherapy antibodies. This critical support and lead-of-faith from CRI in believing in our work when others did not allowed us to 1) generated critical pre-clinical data to secure a larger grant, 2) published a high-impact paper describing how ablation of hypoxia sensitized prostate cancer to immunotherapy, and 3) eventually launch a clinical trial in which prostate and pancreatic cancer patients are now benefiting from this approach. Thank you CRI for helping us all engage the immune system to wipe out cancer!

Professional with expertise in this field

Rating: 5

The ambition and dedication of CRI in addressing the most urgent questions in the field of cancer immunology and immunotherapy have made a difference to the world. I am very grateful to be supported by CRI to pursue an exciting career in the field and be part of the excellent community.

Professional with expertise in this field

Rating: 5

I am an early-career scientist with a strong interest in understanding how tumors evade the immune system during cancer progression and metastasis. The Cancer Research Institute has been on the forefront of immunotherapy research, and decades of work have paid off with exciting results with new immunotherapy treatments. However, not all tumors respond to immunotherapy, and metastasis remains a leading cause of cancer death. The Cancer Research Institute has directly supported my work on understanding how pancreatic cancer regulates the immune system to allow for tumor growth and the spread of the disease. This work has the potential to provide key insights into strategies for activating an anti-tumor immune response. Thank you, Cancer Research Institute!

Professional with expertise in this field

Rating: 5

I am a postdoctoral researcher fortunate to have been supported by the CRI Irvington Postdoctoral Fellowship. It is truly commendable that CRI recognizes the value of basic immunological research, and that it is committed to supporting young researchers like me who are pursuing these questions.

3 SweetDoc

General Member of the Public

Rating: 5

I hope those comprising CRI are interested in 2lbs of stevia curing my uncle's 6 in transition phase to cancer breast tumors. He'd just lost his prostate to cancer, and thought his life was over. Adding the facts 62lbs of flab melted off with no hanging/flabby skin, and type 2 diabetes no longer registering makes this seem like a fairy tale, but those results did happen.

Stevia is very high in alkalinity, I've read that a high alkaline diet= a difficult environment for cancer and other diseases from living inside those bodies, and am hoping that someone at CRI is interested in investigating these valid claims.

1

Professional with expertise in this field

Rating: 5

I am a postdoctoral scientist at Harvard Medical School, studying how the immune system reacts to insults by infections and cancer. CRI is funding my research since the beginning of this year and I am very grateful for this. It is a great honor for me to get awarded a CRI fellowship, which is well-known as a very prestigious fellowship. CRI recognizes the necessity to fund basic research in order to advance the clinic.

Professional with expertise in this field

Rating: 5

As a CRI-funded postdoctoral fellow, I could speak all day about the tireless efforts of the CRI to fund basic and translational research and bring immunotherapy to the clinic. The most significant thing for me is that the CRI awards grants based on scientific merit, regardless of nationality or location of research. Which means that they funded me (a non-American citizen/non-permanent resident) to do cancer research in France. I am greatly indebted to the CRI and its donors for believing in the value of my research, and will continue to work my tail off throughout my career to make their early investment in me a worthwhile one. Thank you CRI!

Professional with expertise in this field

Rating: 5

CRI has played a significant role in my career as a young scientist by funding three years of my postdoctoral research at Caltech. In addition to direct support, I have greatly enjoyed the opportunities CRI has provided to network and collaborate with scientists involved in a very broad range of immunological and cancer research. They do a great job of bringing everyone - from basic researchers to clinicians - to the same table to address really important problems.

Professional with expertise in this field

Rating: 5

The CRI has played an integral part in my development as a scientist and cancer researcher. The organization is perceptive enough to still fund high risk though highly rewarding research. I was lucky enough to receive a postdoctoral research fellowship from them this year to study how intestinal bacteria affect the progression of colorectal cancer using advanced chemical techniques. It is an honor to be included in the outstanding research that is funded and supported by the CRI. A true gem in the cancer research field!

1

Professional with expertise in this field

Rating: 5

The CRI is supporting my project this year, in which we are trying to develop new strategies for cancer immunotherapy. It's such an honour for me, especially knowing that Lieping, one of the major contributors to the newly breakthrough in immunotherapy, was also supported by the CRI in his early years. The work CRI has supported proves that they have done a really great job in pushing the researches in cancer forward during the past decades.

1 Ed__31

Client Served

Rating: 5

The CRI began funding my post-doctoral work this year. This has allowed me to work on understanding the immune response to metastasis, however, through the events the CRI runs they have also allowed me to network with other young cancer immunologists producing numerous contacts and potential collaborations which will help move this work forward.

1 Dmitry K.

Professional with expertise in this field

Rating: 5

More than 15 years ago I had been very lucky to receive a research fellowship from CRI. That support turned out to be very important in allowing me to finish a study that became my modest contribution to the knowledge of differences in gene regulation between mouse and human immune cells. Later on, I became involved in an educational program in tumor immunology in Moscow, Russia. Due to generous CRI support, we were able to invite very best scientists to come to Moscow specifically for teaching. Many students of that program are now successful young researchers advancing the flourishing field of tumor immunology. Over the years I have attended several CRI symposia and had the privilege of personally meeting a number of CRI administrators and employees including its late scientific director Dr.Lloyd Old. I think Dr.Old was an absolutely great scientist and visionary, and all the members of his team are highly professional bright people dedicated to fighting cancer using immunity. CRI is continuing to do a magnificent job in helping cancer immunology research.

Previous Stories

Professional with expertise in this field

Rating: 5

Is a researcher in the field of oncoimmunology, I constantly give CRI top rating for its focused and flexible support and high quality of research and educational programs funded by this remarkable organization. My opinion is based on a number of attempts (both successful and not) to obtain funding from CRI, as well as on impressions from participation in a number of CRI meetings.

Professional with expertise in this field

Rating: 5

The CRI has supported me as a budding researcher in the field of cancer immunotherapy over the past two years. Beyond funding my research in the lab, the CRI has coordinated my interactions with scientists and physicians to inspire new cutting-edge ideas. The CRI also helps to eliminate the disconnect between scientists and patients by setting up meetings with immunotherapy recipients, allowing us to truly see and feel the effect we are having on so many lives. The payoff for their efforts has been fully realized in the last decade, with cancer immunotherapy (their primary focus) being recognized as the Science magazine breakthrough of the year in 2013.

Professional with expertise in this field

Rating: 5

The CRI has been at the forefront of cancer immunology research for decades. The growing success of cancer therapies aimed at the immune system is in no small part due to the efforts of the CRI. As a fellow with CRI funding, I am very grateful for their support, which is allowing me to hone my immunology training for a career in cancer immunology. This organization is not simply a distributor of cash, however. I have been struck by the enthusiasm and optimism of the CRI staff (scientific or otherwise), their desire to engage the public to increase cancer awareness, and their ability to foster a highly collegial environment that is unsurpassed by any other nonprofit I've interacted with. The CRI is doing a great job, and I'm proud to be one of their fellows!

Ian_10

Professional with expertise in this field

Rating: 5

CRI has consistently funded the best people in cancer research to do ground breaking translational research in cancer, and has also provided a cutting edge forum for many years for discussion of the now clearly useful field of cancer immunology.

Michele Pretty Sure A.

Professional with expertise in this field

Rating: 5

The research CRI is currently founding has the potential to save many lives and to greatly increase the knowledge of mechanisms underlying the interplay between tumor cells and the immune system. They are definitively doing an amazing job.

Professional with expertise in this field

Rating: 5

I have been supported by CRI postdoctoral fellowship since 2013, just like hundreds of other researchers CRI supported for decades. Thanks to their efforts, promising immune therapies and drugs have been greatly developed in cancer treatment. Although my research is not directly on clinical, the annual symposium provides great opportunity for me to learn about the latest progress on cancer therapies. Sharing researches with clinicians and other CRI fellows inspire novel ideas and facilitate collaborations.

Professional with expertise in this field

Rating: 5

I am a post-doctoral scientist at UCSF who's research is supported by CRI, for which I am very grateful. I have been extremely impressed with the breadth of research funded by CRI and I firmly believe that CRI does an outstanding job of advancing the treatment of human diseases though advances in basic biology.

Professional with expertise in this field

Rating: 5

Great institute to really support research that makes a difference in cancer diagnosis and treatment. I appreciate the research funds given by CRI to allow us to tackle the immune system for cancer treatment.

Professional with expertise in this field

Rating: 5

I am supported by CRI as a postdoctoral researcher at the University of California, San Francisco. I was ecstatic to start work that will help us learn more about tumor-related inflammation and the damage it can cause. I recently had the opportunity to attend a CRI meeting in New York and was astounded by the quality of work that CRI supports across the country and the passion with which these researchers tackle problems central to cancer treatment. I would encourage you to support this fantastic organization. Thanks!