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2014 Top-Rated Nonprofit

Cancer Research Institute, Inc.

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Nonprofit Overview

Causes: Cancer, Cancer Research, Health, Medical Disciplines Research

Mission: The Cancer Research Institute (CRI) is the world's only nonprofit organization dedicated soley to advancing immunological research leading to the development of immune system-based treatments for cancer. CRI provides funding and coordination to support all levels of research in immunology and tumor immunology, from basic studies to clinical investigation of promising new cancer treatments.

Results: CRI has conducted more than 40 early stage clinical trials of unique cancer vaccines, and has made significant contributions to our knowledge of the human immune response to cancer immunotherapy. CRI researchers have also identified numerous cancer cell markers that are now being tested as targets for immunotherapy. CRI has empowered academic investigators around the world to conduct important clinical discovery, accelerating the translation of new knowledge into treatments for cancer patients.

Target demographics: Under the leadership of our Scientific Advisory Council, which includes 4 Nobel Laureates and 28 members of the National Academy of Sciences, CRI funds academic research in immunology and tumor immunology at universities and health research centers around the world.

Direct beneficiaries per year: Approximately 300 scientists and clinicians in 15 countries

Geographic areas served: National, International

Programs: Clinical Research: *Cancer Vaccine Collaborative, a joint program with the Ludwig Institute for Cancer Research, that supports a network of 19 academic clinical trial sites and immune monitoring laboratories around the world conducting early phase clinical trials of the most promising cancer immunotherapies; *the Cancer Immunotherapy Consortium, an association of more than 70 pharmaceutical & biotech companies and academic institutions engaged in late-stage product development that work together to shape the emerging field of immuno-oncology; *Cancer Vaccine Acceleration Fund, a unique venture philanthropy model designed to partner our clinical trials network with companies and their promising vaccine reagents. Basic Research & Training: *Investigator Award program, providing 4 years of bridge support to newly established laboratories at universities; *Irvington Fellowship Program, provides 3 years of postdoctoral fellowship funding to talented scientists working under the mentorship of leading immunologists; *Predoctoral Pathways program, offering 4-year grants to universities to establish tumor immunology educational curriculum for graduate students.

Community Stories

80 Stories from Volunteers, Donors & Supporters

3 SweetDoc

General Member of the Public

Rating: 5

I hope those comprising CRI are interested in 2lbs of stevia curing my uncle's 6 in transition phase to cancer breast tumors. He'd just lost his prostate to cancer, and thought his life was over. Adding the facts 62lbs of flab melted off with no hanging/flabby skin, and type 2 diabetes no longer registering makes this seem like a fairy tale, but those results did happen.

Stevia is very high in alkalinity, I've read that a high alkaline diet= a difficult environment for cancer and other diseases from living inside those bodies, and am hoping that someone at CRI is interested in investigating these valid claims.

1

Professional with expertise in this field

Rating: 5

I am a postdoctoral scientist at Harvard Medical School, studying how the immune system reacts to insults by infections and cancer. CRI is funding my research since the beginning of this year and I am very grateful for this. It is a great honor for me to get awarded a CRI fellowship, which is well-known as a very prestigious fellowship. CRI recognizes the necessity to fund basic research in order to advance the clinic.

Professional with expertise in this field

Rating: 5

As a CRI-funded postdoctoral fellow, I could speak all day about the tireless efforts of the CRI to fund basic and translational research and bring immunotherapy to the clinic. The most significant thing for me is that the CRI awards grants based on scientific merit, regardless of nationality or location of research. Which means that they funded me (a non-American citizen/non-permanent resident) to do cancer research in France. I am greatly indebted to the CRI and its donors for believing in the value of my research, and will continue to work my tail off throughout my career to make their early investment in me a worthwhile one. Thank you CRI!

Professional with expertise in this field

Rating: 5

CRI has played a significant role in my career as a young scientist by funding three years of my postdoctoral research at Caltech. In addition to direct support, I have greatly enjoyed the opportunities CRI has provided to network and collaborate with scientists involved in a very broad range of immunological and cancer research. They do a great job of bringing everyone - from basic researchers to clinicians - to the same table to address really important problems.

Professional with expertise in this field

Rating: 5

The CRI has played an integral part in my development as a scientist and cancer researcher. The organization is perceptive enough to still fund high risk though highly rewarding research. I was lucky enough to receive a postdoctoral research fellowship from them this year to study how intestinal bacteria affect the progression of colorectal cancer using advanced chemical techniques. It is an honor to be included in the outstanding research that is funded and supported by the CRI. A true gem in the cancer research field!

1

Professional with expertise in this field

Rating: 5

The CRI is supporting my project this year, in which we are trying to develop new strategies for cancer immunotherapy. It's such an honour for me, especially knowing that Lieping, one of the major contributors to the newly breakthrough in immunotherapy, was also supported by the CRI in his early years. The work CRI has supported proves that they have done a really great job in pushing the researches in cancer forward during the past decades.

1 Ed__31

Client Served

Rating: 5

The CRI began funding my post-doctoral work this year. This has allowed me to work on understanding the immune response to metastasis, however, through the events the CRI runs they have also allowed me to network with other young cancer immunologists producing numerous contacts and potential collaborations which will help move this work forward.

1 Dmitry K.

Professional with expertise in this field

Rating: 5

More than 15 years ago I had been very lucky to receive a research fellowship from CRI. That support turned out to be very important in allowing me to finish a study that became my modest contribution to the knowledge of differences in gene regulation between mouse and human immune cells. Later on, I became involved in an educational program in tumor immunology in Moscow, Russia. Due to generous CRI support, we were able to invite very best scientists to come to Moscow specifically for teaching. Many students of that program are now successful young researchers advancing the flourishing field of tumor immunology. Over the years I have attended several CRI symposia and had the privilege of personally meeting a number of CRI administrators and employees including its late scientific director Dr.Lloyd Old. I think Dr.Old was an absolutely great scientist and visionary, and all the members of his team are highly professional bright people dedicated to fighting cancer using immunity. CRI is continuing to do a magnificent job in helping cancer immunology research.

Previous Stories

Professional with expertise in this field

Rating: 5

Is a researcher in the field of oncoimmunology, I constantly give CRI top rating for its focused and flexible support and high quality of research and educational programs funded by this remarkable organization. My opinion is based on a number of attempts (both successful and not) to obtain funding from CRI, as well as on impressions from participation in a number of CRI meetings.

Professional with expertise in this field

Rating: 5

The CRI has supported me as a budding researcher in the field of cancer immunotherapy over the past two years. Beyond funding my research in the lab, the CRI has coordinated my interactions with scientists and physicians to inspire new cutting-edge ideas. The CRI also helps to eliminate the disconnect between scientists and patients by setting up meetings with immunotherapy recipients, allowing us to truly see and feel the effect we are having on so many lives. The payoff for their efforts has been fully realized in the last decade, with cancer immunotherapy (their primary focus) being recognized as the Science magazine breakthrough of the year in 2013.

Professional with expertise in this field

Rating: 5

The CRI has been at the forefront of cancer immunology research for decades. The growing success of cancer therapies aimed at the immune system is in no small part due to the efforts of the CRI. As a fellow with CRI funding, I am very grateful for their support, which is allowing me to hone my immunology training for a career in cancer immunology. This organization is not simply a distributor of cash, however. I have been struck by the enthusiasm and optimism of the CRI staff (scientific or otherwise), their desire to engage the public to increase cancer awareness, and their ability to foster a highly collegial environment that is unsurpassed by any other nonprofit I've interacted with. The CRI is doing a great job, and I'm proud to be one of their fellows!

Ian_10

Professional with expertise in this field

Rating: 5

CRI has consistently funded the best people in cancer research to do ground breaking translational research in cancer, and has also provided a cutting edge forum for many years for discussion of the now clearly useful field of cancer immunology.

Michele Pretty Sure A.

Professional with expertise in this field

Rating: 5

The research CRI is currently founding has the potential to save many lives and to greatly increase the knowledge of mechanisms underlying the interplay between tumor cells and the immune system. They are definitively doing an amazing job.

Professional with expertise in this field

Rating: 5

I have been supported by CRI postdoctoral fellowship since 2013, just like hundreds of other researchers CRI supported for decades. Thanks to their efforts, promising immune therapies and drugs have been greatly developed in cancer treatment. Although my research is not directly on clinical, the annual symposium provides great opportunity for me to learn about the latest progress on cancer therapies. Sharing researches with clinicians and other CRI fellows inspire novel ideas and facilitate collaborations.

Professional with expertise in this field

Rating: 5

I am a post-doctoral scientist at UCSF who's research is supported by CRI, for which I am very grateful. I have been extremely impressed with the breadth of research funded by CRI and I firmly believe that CRI does an outstanding job of advancing the treatment of human diseases though advances in basic biology.

Professional with expertise in this field

Rating: 5

Great institute to really support research that makes a difference in cancer diagnosis and treatment. I appreciate the research funds given by CRI to allow us to tackle the immune system for cancer treatment.

Professional with expertise in this field

Rating: 5

I am supported by CRI as a postdoctoral researcher at the University of California, San Francisco. I was ecstatic to start work that will help us learn more about tumor-related inflammation and the damage it can cause. I recently had the opportunity to attend a CRI meeting in New York and was astounded by the quality of work that CRI supports across the country and the passion with which these researchers tackle problems central to cancer treatment. I would encourage you to support this fantastic organization. Thanks!

Professional with expertise in this field

Rating: 5

As a cancer researcher, I highly endorse the fantastic work done by the Cancer Research Institute (CRI). The CRI is the premier non-profit organization in the realm of cancer immunotherapy, which can lead to durable responses not seen using other therapeutic approaches. (For this reason, cancer immunotherapy was recently highlighted as the Breakthrough of the Year for 2013 by the prestigious journal Science.) In addition to organizing clinical trial information for patients and hosting a fantastic biennial conference for scientists, the CRI funds exceptional trainees and cutting-edge research in order to work towards a cure for cancer. Independent analysis by Charity Navigator reveals that the CRI has earned the top four-star rating, scoring 94% on financial and a perfect 100% on accountability and transparency (http://www.charitynavigator.org/index.cfm?bay=search.summary&orgid=3417#.VEAryktUBD4).

Client Served

Rating: 5

I am a graduate student at the University of California - Berkeley. My doctoral work focuses on the role of the immune system in fighting cancer. In Sept 2013, I was awarded a fellowship from the CRI to fund my research. This fellowship has allowed me the academic and financial freedom to pursue research directly related to human disease.I cannot speak highly enough of the CRI's work. The CRI has supported hundreds of scientists in the fight against cancer through direct research funding. In addition, the CRI organizes various annual symposia to allow scientists and clinicians to share research and discuss collaborative projects. Through these activities, the CRI has made a wonderful contribution to the field of cancer research, and it's work has had a direct impact on the development of novel, promising therapies for the treatment of cancer.

Professional with expertise in this field

Rating: 5

Funding from the CRI allows me to conduct a clinical trial in late stage cervical cancer patients that otherwise have little hope for a cure.

Professional with expertise in this field

Rating: 5

I am a post-doc at The Rockefeller University, and receives CRI post-doc fellowship. The funding from CRI greatly helps my ongoing research in the field of cancer and immunology. Myself also benefits greatly from attending the events organized by CRI, such as the annual international cancer immunotherapy meeting. These events greatly broaden my scientific horizon and provide the changes to collaborate with other scientists in the field to do great science together!