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Causes: Biomedicine & Bioengineering Research, Health
Mission: The mission of this organization is to conduct scientific research aimed at curing or preventing human disease. We will conduct basic research aimed at understanding the fundamental mechanisms of normal biological processes and how these differ in disease states. This will help us to identify new ways to diagnose, prevent or treat human disease. We will also conduct preclinical discovery research into developing and testing novel vaccines and therapeutic agents for human disease.
Programs: 1. Viral immunology. The objective of this program is to conduct research into the mechanisms by which the immune system protects us against viral infections. This research will help us to develop better vaccines and therapeutic agents for viral infections. In addition, it will assist in the design of better immunosuppressive drugs to prevent transplant rejection and autoimmunity, without compromising immunity to viral infections. This program includes pre-clinical research on novel universal influenza vaccine, funded by the national institutes of health. Influenza causes an average of 36,000 deaths and 200,000 hospitalizations per year in the us, while global pandemics have previously killed over 50 million people. We have confimed that, unlike current vaccines, this novel vaccine provides effective protection against multiple different strains of influenza. Our goals are to evaluate the possible side effects, to determine the mechanism by which the vaccine protects against multiple influenza strains and to determine whether the vaccine prevents secondary bacterial infections that often significantly increase mortality.