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Nonprofit Overview

Causes: Cancer, Cancer Research, Health, Medical Disciplines Research

Mission: The Cancer Research Institute (CRI) is the world's only nonprofit organization dedicated soley to advancing immunological research leading to the development of immune system-based treatments for cancer. CRI provides funding and coordination to support all levels of research in immunology and tumor immunology, from basic studies to clinical investigation of promising new cancer treatments.

Results: CRI has conducted more than 40 early stage clinical trials of unique cancer vaccines, and has made significant contributions to our knowledge of the human immune response to cancer immunotherapy. CRI researchers have also identified numerous cancer cell markers that are now being tested as targets for immunotherapy. CRI has empowered academic investigators around the world to conduct important clinical discovery, accelerating the translation of new knowledge into treatments for cancer patients.

Target demographics: Under the leadership of our Scientific Advisory Council, which includes 4 Nobel Laureates and 28 members of the National Academy of Sciences, CRI funds academic research in immunology and tumor immunology at universities and health research centers around the world.

Direct beneficiaries per year: Approximately 300 scientists and clinicians in 15 countries

Geographic areas served: National, International

Programs: Clinical Research: *Cancer Vaccine Collaborative, a joint program with the Ludwig Institute for Cancer Research, that supports a network of 19 academic clinical trial sites and immune monitoring laboratories around the world conducting early phase clinical trials of the most promising cancer immunotherapies; *the Cancer Immunotherapy Consortium, an association of more than 70 pharmaceutical & biotech companies and academic institutions engaged in late-stage product development that work together to shape the emerging field of immuno-oncology; *Cancer Vaccine Acceleration Fund, a unique venture philanthropy model designed to partner our clinical trials network with companies and their promising vaccine reagents. Basic Research & Training: *Investigator Award program, providing 4 years of bridge support to newly established laboratories at universities; *Irvington Fellowship Program, provides 3 years of postdoctoral fellowship funding to talented scientists working under the mentorship of leading immunologists; *Predoctoral Pathways program, offering 4-year grants to universities to establish tumor immunology educational curriculum for graduate students.

Community Stories

60 Stories from Volunteers, Donors & Supporters

Professional with expertise in this field

Rating: 5

I have been supported by CRI postdoctoral fellowship since 2013, just like hundreds of other researchers CRI supported for decades. Thanks to their efforts, promising immune therapies and drugs have been greatly developed in cancer treatment. Although my research is not directly on clinical, the annual symposium provides great opportunity for me to learn about the latest progress on cancer therapies. Sharing researches with clinicians and other CRI fellows inspire novel ideas and facilitate collaborations.

Professional with expertise in this field

Rating: 5

I am a post-doctoral scientist at UCSF who's research is supported by CRI, for which I am very grateful. I have been extremely impressed with the breadth of research funded by CRI and I firmly believe that CRI does an outstanding job of advancing the treatment of human diseases though advances in basic biology.

Professional with expertise in this field

Rating: 5

Great institute to really support research that makes a difference in cancer diagnosis and treatment. I appreciate the research funds given by CRI to allow us to tackle the immune system for cancer treatment.

Professional with expertise in this field

Rating: 5

I am supported by CRI as a postdoctoral researcher at the University of California, San Francisco. I was ecstatic to start work that will help us learn more about tumor-related inflammation and the damage it can cause. I recently had the opportunity to attend a CRI meeting in New York and was astounded by the quality of work that CRI supports across the country and the passion with which these researchers tackle problems central to cancer treatment. I would encourage you to support this fantastic organization. Thanks!

Professional with expertise in this field

Rating: 5

As a cancer researcher, I highly endorse the fantastic work done by the Cancer Research Institute (CRI). The CRI is the premier non-profit organization in the realm of cancer immunotherapy, which can lead to durable responses not seen using other therapeutic approaches. (For this reason, cancer immunotherapy was recently highlighted as the Breakthrough of the Year for 2013 by the prestigious journal Science.) In addition to organizing clinical trial information for patients and hosting a fantastic biennial conference for scientists, the CRI funds exceptional trainees and cutting-edge research in order to work towards a cure for cancer. Independent analysis by Charity Navigator reveals that the CRI has earned the top four-star rating, scoring 94% on financial and a perfect 100% on accountability and transparency (http://www.charitynavigator.org/index.cfm?bay=search.summary&orgid=3417#.VEAryktUBD4).

Professional with expertise in this field

Rating: 5

Funding from the CRI allows me to conduct a clinical trial in late stage cervical cancer patients that otherwise have little hope for a cure.

Professional with expertise in this field

Rating: 5

I am a post-doc at The Rockefeller University, and receives CRI post-doc fellowship. The funding from CRI greatly helps my ongoing research in the field of cancer and immunology. Myself also benefits greatly from attending the events organized by CRI, such as the annual international cancer immunotherapy meeting. These events greatly broaden my scientific horizon and provide the changes to collaborate with other scientists in the field to do great science together!

Professional with expertise in this field

Rating: 5

The Cancer Research Institute (CRI) has funded my research as a postdoctoral fellow at the University of Washington since 2013.

Professional with expertise in this field

Rating: 5

The CRI has supported my postdoctoral research since 2012 through one of their competitive fellowship awards. Thanks to this amazing support we have developed new therapeutic strategies to re-direct the immune system against aggressive malignancies such as ovarian cancer. Transforming devastating cancers into curable diseases will only be possible through immunotherapy, and the CRI is substantially leading this vital task.

Professional with expertise in this field

Rating: 5

I was awarded a CRI fellowship to conduct my research at the University of Pennsylvania. This incredibly generous support for basic research that has really laid the foundation for my postdoctoral career, and has allowed me to focus on developing as a scientist. This funding will allow our research team to further develop our basic understanding of how immunotherapy works in cancer, which will hopefully continue to shape the way we approach this therapy in patients.