Cancer Research Institute, Inc.

Rating: 4.99 stars   80 reviews

Issues: Health, Cancer

Location: One Exchange Plaza, 55 Broadway Suite 1802 New York NY 10006 USA

Mission: The Cancer Research Institute (CRI) is the world's only nonprofit organization dedicated soley to advancing immunological research leading to the development of immune system-based treatments for cancer. CRI provides funding and coordination to support all levels of research in immunology and tumor immunology, from basic studies to clinical investigation of promising new cancer treatments.
Results: CRI has conducted more than 40 early stage clinical trials of unique cancer vaccines, and has made significant contributions to our knowledge of the human immune response to cancer immunotherapy. CRI researchers have also identified numerous cancer cell markers that are now being tested as targets for immunotherapy. CRI has empowered academic investigators around the world to conduct important clinical discovery, accelerating the translation of new knowledge into treatments for cancer patients.
Target demographics: Under the leadership of our Scientific Advisory Council, which includes 4 Nobel Laureates and 28 members of the National Academy of Sciences, CRI funds academic research in immunology and tumor immunology at universities and health research centers around the world.
Direct beneficiaries per year: Approximately 300 scientists and clinicians in 15 countries
Geographic areas served: National, International
Programs: Clinical Research: *Cancer Vaccine Collaborative, a joint program with the Ludwig Institute for Cancer Research, that supports a network of 19 academic clinical trial sites and immune monitoring laboratories around the world conducting early phase clinical trials of the most promising cancer immunotherapies; *the Cancer Immunotherapy Consortium, an association of more than 70 pharmaceutical & biotech companies and academic institutions engaged in late-stage product development that work together to shape the emerging field of immuno-oncology; *Cancer Vaccine Acceleration Fund, a unique venture philanthropy model designed to partner our clinical trials network with companies and their promising vaccine reagents. Basic Research & Training: *Investigator Award program, providing 4 years of bridge support to newly established laboratories at universities; *Irvington Fellowship Program, provides 3 years of postdoctoral fellowship funding to talented scientists working under the mentorship of leading immunologists; *Predoctoral Pathways program, offering 4-year grants to universities to establish tumor immunology educational curriculum for graduate students.
2014 Top-Rated Nonprofit
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Community Reviews

Role: Professional with expertise in this field
Rating: 5 stars  

The Cancer Research Institute (CRI) has funded my research as a postdoctoral fellow at the University of Washington since 2013.

How does this organization compare with others in the same sector?

Very Well

How much of an impact do you think this organization has?

Life-changing

Will you recommend this organization to others?

Definitely

When was your last experience with this nonprofit?

2014

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Role: Professional with expertise in this field
Rating: 5 stars  

The CRI has supported my postdoctoral research since 2012 through one of their competitive fellowship awards. Thanks to this amazing support we have developed new therapeutic strategies to re-direct the immune system against aggressive malignancies such as ovarian cancer. Transforming devastating cancers into curable diseases will only be possible through immunotherapy, and the CRI is substantially leading this vital task.

How does this organization compare with others in the same sector?

Very Well

How much of an impact do you think this organization has?

Life-changing

Will you recommend this organization to others?

Definitely

When was your last experience with this nonprofit?

2014

Was this review helpful? 
Role: Professional with expertise in this field
Rating: 5 stars  

I was awarded a CRI fellowship to conduct my research at the University of Pennsylvania. This incredibly generous support for basic research that has really laid the foundation for my postdoctoral career, and has allowed me to focus on developing as a scientist. This funding will allow our research team to further develop our basic understanding of how immunotherapy works in cancer, which will hopefully continue to shape the way we approach this therapy in patients.

How does this organization compare with others in the same sector?

Very Well

How much of an impact do you think this organization has?

Life-changing

Will you recommend this organization to others?

Definitely

When was your last experience with this nonprofit?

2014

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Role: Professional with expertise in this field
Rating: 5 stars  

They give me very good support on my research and are together with me all the time. With the help from them, I made good progress with my research, which provides further understanding of B cell lymphomas.

How does this organization compare with others in the same sector?

Very Well

How much of an impact do you think this organization has?

A lot

Will you recommend this organization to others?

Definitely

When was your last experience with this nonprofit?

2014

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Rating: 5 stars  

I was awarded CRI fellowship to conduct my research at the University of Chicago. This helped us to identify pathways critical to leukemias and lymphomas.

How does this organization compare with others in the same sector?

Very Well

How much of an impact do you think this organization has?

Life-changing

Will you recommend this organization to others?

Definitely

When was your last experience with this nonprofit?

2012

Was this review helpful? 
Rating: 5 stars  

CRI's generous and continued support of our research in cancer immunology and cancer immunotherapy helped us to establish a sustainable clinical research and teaching/training program in the field. New students and young researchers were introduced to the field as MD/PhD students and young faculty. CRI's CVC helped to establish a Clinical Trials Center at the University of Zurich. Ultra-lean management and great communication skills with an outstanding scientific faculty advising characterize CRI's success as a non-profit organization focused on Cancer Immunology and Cancer Immunotherapy.

How does this organization compare with others in the same sector?

Very Well

How much of an impact do you think this organization has?

Life-changing

Will you recommend this organization to others?

Definitely

When was your last experience with this nonprofit?

2012

Was this review helpful? 
Role: Professional with expertise in this field
Rating: 5 stars  

I was awarded a CRI postdoc fellowship a few years ago, which turns me from a scientific worker to a scientist. The critical difference between these two is that the later endowed with a great passion and motivation for research which grew in me during this postdoctoral training phases. Without the support from CRI, this transformation will not likely happen. Thank CRI for training young people in the cancer research field, and I believe our research will eventually provide great benefits for cancer patients.

I've personally experienced the results of this organization in...

scientific meeting

If I had to make changes to this organization, I would...

I think CRI has done superior job for cancer research community and cancer patients

How does this organization compare with others in the same sector?

Very Well

How much of an impact do you think this organization has?

Life-changing

Will you recommend this organization to others?

Definitely

What is unique about this organization?

great vision of organizer and dedicated stuff member

When was your last experience with this nonprofit?

2009

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Role: Professional with expertise in this field
Rating: 5 stars  

During my postdoctoral studies at the section of Immunobiology at Yale Medical School I have been a CRI fellow studying the transcriptional regulation of cytokine genes driving the differentiation processes of T helper cells. During that period, and having peace of mind because CRI was funding my research, we were able to advance our knowledge about gene regulation and show that the three dimensional structure of the genome affects the expression profile of a locus. More importantly others have shown that proximity of gene loci in the 3D nucleus increase the probability for a translocation event usually found in leukemia and tumors.
The funding I have received during my postdoctoral studies was of fundamental importance and helped me get an Assistant Professorship. And again my good angel CRI was there to support my research with an Investigator award. This gave a kickstart to my career and my first steps as an independent investigator. I am really proud being part of this team of people who are dedicated and hard working with the ultimate goal of conquering cancer.

I've personally experienced the results of this organization in...

setting up the fundamental for a new career in molecular immunology and continued to passionately work on that.

If I had to make changes to this organization, I would...

try to make it even more familiar to the public.

How does this organization compare with others in the same sector?

Very Well

How much of an impact do you think this organization has?

Life-changing

Will you recommend this organization to others?

Definitely

What is unique about this organization?

The quality of people that work for it. They have a clear vision and they do everything to support it not as part of their job but as part of their life.

When was your last experience with this nonprofit?

2011

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Role: Professional with expertise in this field
Rating: 5 stars  

I was the recipient of a CRI postdoctoral fellowship award that funded my research in the function of the innate immune system during aging at MIT. Because of the generous support of CRI, I was able to make important discoveries that I anticipate will help to form the foundation of further study in age-dependent dynamics of signaling pathways that regulate the immune response later in life. Throughout my years as a CRI fellow, I have found the staff at CRI to be professional, supportive, and truly dedicated to the cause of advancing scientific knowledge toward the goal of eliminating cancer. My heartfelt thanks goes to CRI, and I would strongly recommend CRI as a benefactor of those seeking to support biomedical research.

I've personally experienced the results of this organization in...

financial support for my work in aging and immunity.

If I had to make changes to this organization, I would...

raise their profile so that more people were aware of their outstanding work.

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Role: Professional with expertise in this field
Rating: 5 stars  

The Cancer Research Institute by wisely selecting and generously supporting investigators and projects on cancer research has immensely contributed to advance our understanding of malignancies, thus paving the way for novel therapies. With the support of the CRI we have developed new MHC-peptide based reagents that allow improved detection and isolation of antigen-specific CD8+ and CD8+ T lymphocytes. We endeavour after final optimization to make these reagents generally available, thus contributing to better monitor and understand cancer specific T cell immunity.

I've personally experienced the results of this organization in...

The support of the CRI was critical for our efforts, which without it may have afiled.

If I had to make changes to this organization, I would...

The programs seem well balanced. In terms of comparing and validating diagnostic and monitoring tools wider and more stringent comparisons might be useful.

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