BeatSarcoma

Rating: 4.94 stars   18 reviews

Issues: Health, Cancer

Location: 143 28th St Suite 4 San Francisco CA 94131 USA

Mission: Sarcoma is a form of cancer that arises in the connective tissues. It affects primarily children and young adults. They are hard to diagnose, hard to detect and hard to treat. Biopsy is the only diagnostic tool and surgery often the only curative treatment. Many sarcomas resist current cancer treatments, simply because they are little understood by researchers. - 20% of childhood cancers are sarcomas. They affect also many young adults. Sarcoma destroys so many lives before they have had time to blossom. - Sarcoma gets less than 1% of cancer research funds - this is not enough. Sarcoma research is years behind compared to that for other cancers. This is the situation we would like to change - and reestablish a working cycle between basic research => transational research => clinical research (often funded by the industry). The middle link seems broken for sarcoma.
Programs: In 2008, we are planning on funding the following research program - through a variety of initiatives. We are also developing a Kid's Program and to date have distributed 15 books to children with sarcoma in hospitals. What is the problem One of the biggest questions in sarcoma treatment is accurately diagnosing the type of sarcoma and its aggressiveness. This is important because more specific and accurate pathology translate into better treatment plans. Being able to reliably and consistently diagnose the cancer is the first major step toward a reliable and consistent set of solutions. A team of world-class experts couldn't agree on a single diagnoses nor provide one recommendation based on a clear set of data to our founder. What does the solution look like? It requires establishing a link between the biology of sarcoma cells and their associated patient outcomes. Such a link is called a correlation. With this information, scientists will better understand the biologic factors that help predict patient outcomes. This is what Dr. Amreen Husain and her team would like to do, with your help. Specifically, how is this done? These biologic factors are called histopathologic criteria. Histopathology is the microscopic study of diseased tissue. It reveals the types of cells present in abnormal tissue and permits accurate diagnosis, including a measure of the aggressiveness of the disease. The analysis results in a list of histopathologic criteria. Today, for sarcoma, these criteria are insufficient. It is common for a patient to get as many recommendations as there are physicians that studied their pathology slides. This can be dangerous as the histopathologic criteria assist the clinician in deciding on the best course of action. In order to gain such a deep understanding, scientists need a lot of examples - eg. a lot of sarcoma cell samples with associated clinical information. Using gene and protein microarrays, researchers can study the biology of these cells and see if histopathologic patterns appear for any given clinical outcome. How will this help patients? A large study such as this one really has the potential to have a large impact on the future of sarcoma research and eventually clinical care. 1) It tells us which biologic factors are relevant to the clinical outcome - scientists won't waste time on the ones that aren't. 2) It tells us to what extent each biologic factor can be associated with a given outcome. The factors that most strongly correlate with a bad outcome will make ideal targets for future treatments. The information will also help oncologists make treatment recommendations - the more aggressive the cancer, the more aggressive the treatment. This work has been done for other types of cancer but there are no large and comprehensive tissue banks with clinical information for sarcoma. One of the goals of the project coordinated at Stanford is to expand tissue collection, banking and analysis of all types of sarcoma to help physicians better predict clinical outcomes.
2009 Top-Rated Nonprofit
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Community Reviews

Rating: 5 stars  

6 people found this review helpful

I admire the founder's take on life after surviving sarcoma and her devotion to help beating this disease. With very scarce resources the organization has generated visibility and awareness about sarcoma, thanks to the ingenuity of a small group of committed and energetic people.

I've personally experienced the results of this organization in...

Awareness about sarcoma.

What I've enjoyed the most about my experience with this nonprofit is...

The fun and original events.

When was your last experience with this nonprofit?

2009-6-01

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Rating: 5 stars  

9 people found this review helpful

The distance covered by BeatSarcoma since it was founded is astonishing. A small, dedicated, highly professional group of individuals are responsible for this success. The events are creative & fun, and I enjoy them that much more because I know that every dime I give BeatSarcoma is used to make a real difference. Nothing is wasted on the path to beating sarcoma.

I've personally experienced the results of this organization in...

the respect and overwhelmingly positive response they've earned from top professionals working against sarcoma as well as the general public.

What I've enjoyed the most about my experience with this nonprofit is...

the amount of research and thought that goes into each step in their growth, and the way they make their volunteers and donors feel valued.

The kinds of staff and volunteers that I met were...

passionate & professional.

If this organization had 10 million bucks, it could...

skyrocket.

When was your last experience with this nonprofit?

2009-1-01

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Rating: 5 stars  

9 people found this review helpful

BeatSarcoma's goal makes perfect sense and deserves support and visibility. This not-so-well-know disease is kind of left-behind by the medical research effort and BeatSarcoma is just trying to overturn this situation. Besides research effort, BeatSarcoma tries to alleviate the pain the people affected by sarcoma have to bear. This ambitious goal is well served by an effective leader. She manages to raise interest by successful and fun events. Her great human skills, also enlightened by her own experience as a sarcoma survivor, just work magic: everyone becomes a supporter. All this non-profit needs is to gain visibility, with this it can really hope to beat sarcoma.

I've personally experienced the results of this organization in...

the ambitious events organised to increase awareness and raise funds.

What I've enjoyed the most about my experience with this nonprofit is...

its leader.

If this organization had 10 million bucks, it could...

give hope to people suffering from sarcoma to get rid of sarcoma for good.

When was your last experience with this nonprofit?

2009-1-01

Was this review helpful?