BeatSarcoma

Rating: 4.94 stars   18 reviews

Issues: Health, Cancer

Location: 143 28th St Suite 4 San Francisco CA 94131 USA

Mission: Sarcoma is a form of cancer that arises in the connective tissues. It affects primarily children and young adults. They are hard to diagnose, hard to detect and hard to treat. Biopsy is the only diagnostic tool and surgery often the only curative treatment. Many sarcomas resist current cancer treatments, simply because they are little understood by researchers. - 20% of childhood cancers are sarcomas. They affect also many young adults. Sarcoma destroys so many lives before they have had time to blossom. - Sarcoma gets less than 1% of cancer research funds - this is not enough. Sarcoma research is years behind compared to that for other cancers. This is the situation we would like to change - and reestablish a working cycle between basic research => transational research => clinical research (often funded by the industry). The middle link seems broken for sarcoma.
Programs: In 2008, we are planning on funding the following research program - through a variety of initiatives. We are also developing a Kid's Program and to date have distributed 15 books to children with sarcoma in hospitals. What is the problem One of the biggest questions in sarcoma treatment is accurately diagnosing the type of sarcoma and its aggressiveness. This is important because more specific and accurate pathology translate into better treatment plans. Being able to reliably and consistently diagnose the cancer is the first major step toward a reliable and consistent set of solutions. A team of world-class experts couldn't agree on a single diagnoses nor provide one recommendation based on a clear set of data to our founder. What does the solution look like? It requires establishing a link between the biology of sarcoma cells and their associated patient outcomes. Such a link is called a correlation. With this information, scientists will better understand the biologic factors that help predict patient outcomes. This is what Dr. Amreen Husain and her team would like to do, with your help. Specifically, how is this done? These biologic factors are called histopathologic criteria. Histopathology is the microscopic study of diseased tissue. It reveals the types of cells present in abnormal tissue and permits accurate diagnosis, including a measure of the aggressiveness of the disease. The analysis results in a list of histopathologic criteria. Today, for sarcoma, these criteria are insufficient. It is common for a patient to get as many recommendations as there are physicians that studied their pathology slides. This can be dangerous as the histopathologic criteria assist the clinician in deciding on the best course of action. In order to gain such a deep understanding, scientists need a lot of examples - eg. a lot of sarcoma cell samples with associated clinical information. Using gene and protein microarrays, researchers can study the biology of these cells and see if histopathologic patterns appear for any given clinical outcome. How will this help patients? A large study such as this one really has the potential to have a large impact on the future of sarcoma research and eventually clinical care. 1) It tells us which biologic factors are relevant to the clinical outcome - scientists won't waste time on the ones that aren't. 2) It tells us to what extent each biologic factor can be associated with a given outcome. The factors that most strongly correlate with a bad outcome will make ideal targets for future treatments. The information will also help oncologists make treatment recommendations - the more aggressive the cancer, the more aggressive the treatment. This work has been done for other types of cancer but there are no large and comprehensive tissue banks with clinical information for sarcoma. One of the goals of the project coordinated at Stanford is to expand tissue collection, banking and analysis of all types of sarcoma to help physicians better predict clinical outcomes.
2009 Top-Rated Nonprofit
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Community Reviews

Rating: 5 stars  

8 people found this review helpful

Nat Criou has done an amazing job running BeatSarcoma. She works tirelessly to generate awareness of this type of cancer and has touched many people's lives with her positive energy. I'm always impressed by her strength and energy.

I've personally experienced the results of this organization in...

how organized the group is with their many different activities to generate awareness.

If I had to make changes to this organization, I would...

What I've enjoyed the most about my experience with this nonprofit is...

receiving emails about their activities and updates on their progress.

Ways to make it better...

I lived in SF and could participate in the activities.

In my opinion, the biggest challenges facing this organization are...

awareness of this type of cancer.

One thing I'd also say is that...

Nat Criou is amazing!

When was your last experience with this nonprofit?

2009-4-01

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Rating: 5 stars  

11 people found this review helpful

The Beat Sarcoma Cup is a top notched well organized and well run benifit sailing regatta that Nathalie Criou has organized with the help of Richmond Yacht Club. Nathalie has helped to shed light on a type of cancer and has oped many eyes to a disease that needs so much attention in medical research to help find a cure. If you are a sailor and want to help in some small way, find a boat, find a ride and come help for a cure.

I've personally experienced the results of this organization in...

friends and family who have dealt with this form of cancer.

If I had to make changes to this organization, I would...

not be able to do near as good of a job as Nathalie Criou has done

What I've enjoyed the most about my experience with this nonprofit is...

what the organization does for benifits to bring awarness to their cause.

The kinds of staff and volunteers that I met were...

FIRST RATE

If this organization had 10 million bucks, it could...

countinue to serve the cause in 10 million different ways.

Ways to make it better...

I had the time to volunteer for the organization

In my opinion, the biggest challenges facing this organization are...

simply awarness.

One thing I'd also say is that...

Nat is simply doing the best job.

When was your last experience with this nonprofit?

2008-9-01

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Rating: 5 stars  

10 people found this review helpful

When you participate in BeatSarcoma events you can't help but want to help, and you can't help but have fun. The organizers make it easy to do both. Last year was the first sailboat regatta, with all proceeds going to research. You should have felt the vibe! The sponsoring yacht club has a winning formula for big regattas, and this event can't help but grow. We were so excited by it that we are going to be a sponsor this year.

I've personally experienced the results of this organization in...

Generating awareness for a less-well-known disease.

If I had to make changes to this organization, I would...

What I've enjoyed the most about my experience with this nonprofit is...

The feeling of being part of something truly helpful.

The kinds of staff and volunteers that I met were...

Very friendly and cheerful, not downcast or pushy.

Ways to make it better...

If I had thought of being a sponsor or donating prizes before last year's event.

In my opinion, the biggest challenges facing this organization are...

One thing I'd also say is that...

When was your last experience with this nonprofit?

2009-7-01

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